Dados do Trabalho

Título

PRIMARY BLADDER ADENOCARCINOMA: LONG-TERM FOLLOW-UP SERIES FROM A HIGH-VOLUME ONCOLOGICAL CENTER

Introdução e Objetivo

Long-term oncologic data on patients undergoing radical cystectomy for non-metastatic primary bladder adenocarcinoma (BA) are limited. We assessed patients receiving radical cystectomy at a high-volume terciary oncological Institution.

Método

We analyzed medical records of 40 patients with primary bladder adenocarcinoma between january 2008 and july 2023 at a high-volume oncologic center (Insitute of Cancer of Sao Paulo, Brazil). Clinical and pathologic, and survival data at the latest follow-up were collected. Clinical recurrence-free survival, cancer-specific mortality and overall survival were investigate using Kaplan-Meier survival curves and comparated with urothelial carcinoma .

Resultados

The study is a clinicopathologic report on 40 patients with primary adenocarcinoma of the urinary bladder and urachus. The mean age was 62 (12.64) years, 8 cases with urachal tumors, 3.2% with concomitant carcinoma in situ , 25.6% with lymphovascular invasion. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. 16 patients presented recurrency. The Kaplan Meyer curve was illustrated in figure 1 and compare the overall survival of adenocarcinoma with urothelial carcinoma.

Conclusão

Patients with primary adenocarcinoma of the bladder have epidemiological profile different from urothelial carcinoma , and have lower mortality than patients with urothelial cance